Safety, Pharmacokinetics, and Mosquito‐Lethal Effects of Ivermectin in Combination With Dihydroartemisinin‐Piperaquine and Primaquine in Healthy Adult Thai Subjects

Mass administration of antimalarial drugs and ivermectin are being considered as potential accelerators of malaria elimination. The safety, tolerability, pharmacokinetics, and mosquito‐lethal effects of combinations of ivermectin, dihydroartemisinin‐piperaquine, and primaquine were evaluated. Coadmi...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Kobylinski, Kevin C., Jittamala, Podjanee, Hanboonkunupakarn, Borimas, Pukrittayakamee, Sasithon, Pantuwatana, Kanchana, Phasomkusolsil, Siriporn, Davidson, Silas A., Winterberg, Markus, Hoglund, Richard M., Mukaka, Mavuto, van der Pluijm, Rob W., Dondorp, Arjen, Day, Nicholas P.J., White, Nicholas J., Tarning, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285759/
https://ncbi.nlm.nih.gov/pubmed/31697848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1716
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