Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults

Artemisinin-based combination therapies (ACTs) have contributed substantially to the global decline in Plasmodium falciparum morbidity and mortality, but resistance to artemisinins and their partner drugs is increasing in Southeast Asia, threatening malaria control. New antimalarial compounds will n...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Hanboonkunupakarn, Borimas, van der Pluijm, Rob W., Hoglund, Richard, Pukrittayakamee, Sasithon, Winterberg, Markus, Mukaka, Mavuto, Waithira, Naomi, Chotivanich, Kesinee, Singhasivanon, Pratap, White, Nicholas J., Dondorp, Arjen M., Tarning, Joel, Jittamala, Podjanee
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658739/
https://ncbi.nlm.nih.gov/pubmed/31182525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00060-19
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