Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults

Artemisinin-based combination therapies (ACTs) have contributed substantially to the global decline in Plasmodium falciparum morbidity and mortality, but resistance to artemisinins and their partner drugs is increasing in Southeast Asia, threatening malaria control. New antimalarial compounds will n...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hanboonkunupakarn, Borimas, van der Pluijm, Rob W., Hoglund, Richard, Pukrittayakamee, Sasithon, Winterberg, Markus, Mukaka, Mavuto, Waithira, Naomi, Chotivanich, Kesinee, Singhasivanon, Pratap, White, Nicholas J., Dondorp, Arjen M., Tarning, Joel, Jittamala, Podjanee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658739/
https://ncbi.nlm.nih.gov/pubmed/31182525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00060-19
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