Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults

Artemisinin-based combination therapies (ACTs) have contributed substantially to the global decline in Plasmodium falciparum morbidity and mortality, but resistance to artemisinins and their partner drugs is increasing in Southeast Asia, threatening malaria control. New antimalarial compounds will n...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Hanboonkunupakarn, Borimas, van der Pluijm, Rob W., Hoglund, Richard, Pukrittayakamee, Sasithon, Winterberg, Markus, Mukaka, Mavuto, Waithira, Naomi, Chotivanich, Kesinee, Singhasivanon, Pratap, White, Nicholas J., Dondorp, Arjen M., Tarning, Joel, Jittamala, Podjanee
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658739/
https://ncbi.nlm.nih.gov/pubmed/31182525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00060-19
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