Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults

Artemisinin-based combination therapies (ACTs) have contributed substantially to the global decline in Plasmodium falciparum morbidity and mortality, but resistance to artemisinins and their partner drugs is increasing in Southeast Asia, threatening malaria control. New antimalarial compounds will n...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Hanboonkunupakarn, Borimas, van der Pluijm, Rob W., Hoglund, Richard, Pukrittayakamee, Sasithon, Winterberg, Markus, Mukaka, Mavuto, Waithira, Naomi, Chotivanich, Kesinee, Singhasivanon, Pratap, White, Nicholas J., Dondorp, Arjen M., Tarning, Joel, Jittamala, Podjanee
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658739/
https://ncbi.nlm.nih.gov/pubmed/31182525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00060-19
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