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1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of Azides

The diazo group has untapped utility in chemical biology. The tolerance of stabilized diazo groups to cellular metabolism is comparable to that of azido groups. Yet, chemoselectivity has been elusive, as both groups undergo 1,3-dipolar cycloadditions with strained alkynes. Removing strain and tuning...

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Bibliographische Detailangaben
Veröffentlicht in:Org Lett
Hauptverfasser: Aronoff, Matthew R., Gold, Brian, Raines, Ronald T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141246/
https://ncbi.nlm.nih.gov/pubmed/26981746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00278
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