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Diazo Compounds as Highly Tunable Reactants in 1,3-Dipolar Cycloaddition Reactions with Cycloalkynes()

Diazo compounds, which can be accessed directly from azides by deimidogenation, are shown to be extremely versatile dipoles in 1,3-dipolar cycloaddition reactions with a cyclooctyne. The reactivity of a diazo compound can be much greater or much less than its azide analog, and is enhanced markedly i...

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Bibliographic Details
Main Authors: McGrath, Nicholas A., Raines, Ronald T.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513925/
https://ncbi.nlm.nih.gov/pubmed/23227302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SC20806G
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