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1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of Azides

The diazo group has untapped utility in chemical biology. The tolerance of stabilized diazo groups to cellular metabolism is comparable to that of azido groups. Yet, chemoselectivity has been elusive, as both groups undergo 1,3-dipolar cycloadditions with strained alkynes. Removing strain and tuning...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Aronoff, Matthew R., Gold, Brian, Raines, Ronald T.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141246/
https://ncbi.nlm.nih.gov/pubmed/26981746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00278
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