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A Bayesian dose-finding design incorporating toxicity data from multiple treatment cycles
Phase I oncology trials are designed to identify a safe dose with an acceptable toxicity profile. The dose is typically determined based on the probability of severe toxicity observed during the first treatment cycle, although patients continue to receive treatment for multiple cycles. In addition,...
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| I publikationen: | Stat Med |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5138146/ https://ncbi.nlm.nih.gov/pubmed/27633877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7134 |
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