Loading...
Repeated measures dose-finding design with time trend detection in the presence of correlated toxicity data
BACKGROUND: Phase I trials are designed to determine the safety, tolerability and recommended phase 2 dose of therapeutic agents for subsequent testing. The dose finding paradigm has thus traditionally focused on identifying the maximum tolerable dose of an agent or combination therapy under the ass...
Saved in:
| Published in: | Clin Trials |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714674/ https://ncbi.nlm.nih.gov/pubmed/28764555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774517723829 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|