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How to design a dose-finding study on combined agents: Choice of design and development of R functions
BACKGROUND: In oncology, the aim of dose-finding phase I studies is to find the maximum tolerated dose for further studies. The use of combinations of two or more agents is increasing. Several dose-finding designs have been proposed for this situation. Numerous publications have however pointed out...
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| Publicado no: | PLoS One |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6844553/ https://ncbi.nlm.nih.gov/pubmed/31710632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224940 |
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