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The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the Kras(G12D);Pdx1-Cre (KC) mouse model of pancreatic cancer

Because the 5-year survival rate for pancreatic cancer remains under 10%, new drugs are needed for the prevention and treatment of this devastating disease. Patients with chronic pancreatitis have a 12-fold higher risk of developing pancreatic cancer. LSL-Kras(G12D/+);Pdx-1-Cre (KC) mice replicate t...

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發表在:Carcinogenesis
Main Authors: Leal, Ana S., Sporn, Michael B., Pioli, Patricia A., Liby, Karen T.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137262/
https://ncbi.nlm.nih.gov/pubmed/27659181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw099
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