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The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the Kras(G12D);Pdx1-Cre (KC) mouse model of pancreatic cancer
Because the 5-year survival rate for pancreatic cancer remains under 10%, new drugs are needed for the prevention and treatment of this devastating disease. Patients with chronic pancreatitis have a 12-fold higher risk of developing pancreatic cancer. LSL-Kras(G12D/+);Pdx-1-Cre (KC) mice replicate t...
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| Gepubliceerd in: | Carcinogenesis |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5137262/ https://ncbi.nlm.nih.gov/pubmed/27659181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw099 |
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