The Triterpenoid CDDO-Imidazolide Confers Potent Protection against Hyperoxic Acute Lung Injury in Mice

Rationale: Oxygen supplementation (e.g., hyperoxia) is used to support critically ill patients with noninfectious and infectious acute lung injury (ALI); however, hyperoxia exposure can potentially further contribute to and/or perpetuate preexisting ALI. Thus, developing novel therapeutic agents to...

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Detalhes bibliográficos
Main Authors: Reddy, Narsa M., Suryanaraya, Vegiraju, Yates, Melinda S., Kleeberger, Steven R., Hassoun, Paul M., Yamamoto, Masayuki, Liby, Karen T., Sporn, Michael B., Kensler, Thomas W., Reddy, Sekhar P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
C. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773914/
https://ncbi.nlm.nih.gov/pubmed/19679692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200905-0670OC
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