The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia reperfusion injury in mice

Acute kidney injury (AKI) caused by ischemia reperfusion is a major clinical problem in both native and transplanted kidneys. We previously showed that deficiency of Nrf2, a potent bZIP transcription factor that binds to the antioxidant response element, enhances susceptibility to experimental ische...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Liu, Manchang, Reddy, Narsa M., Higbee, Elizabeth M., Potteti, Haranatha R., Noel, Sanjeev, Racusen, Lorraine, Kensler, Thomas W., Sporn, Michael B., Reddy, Sekhar P., Rabb, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282962/
https://ncbi.nlm.nih.gov/pubmed/24088953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.357
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