T Lymphocyte–Specific Activation of Nrf2 Protects from AKI

T lymphocytes are established mediators of ischemia reperfusion (IR)–induced AKI, but traditional immune principles do not explain their mechanism of early action in the absence of alloantigen. Nrf2 is a transcription factor that is crucial for cytoprotective gene expression and is generally thought...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Noel, Sanjeev, Martina, Maria N., Bandapalle, Samatha, Racusen, Lorraine C., Potteti, Haranatha R., Hamad, Abdel R.A., Reddy, Sekhar P., Rabb, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657838/
https://ncbi.nlm.nih.gov/pubmed/26293820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014100978
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