Nrf2-AKT interactions regulate heme oxygenase 1 expression in kidney epithelia during hypoxia and hypoxia-reoxygenation

Ischemia-reperfusion (IR)-induced kidney injury is a major clinical problem, but its underlying mechanisms remain unclear. The transcription factor known as nuclear factor, erythroid 2-like 2 (NFE2L2 or Nrf2) is crucial for protection against oxidative stress generated by pro-oxidant insults. We hav...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Potteti, Haranatha R., Tamatam, Chandramohan R., Marreddy, Rakesh, Reddy, Narsa M., Noel, Sanjeev, Rabb, Hamid, Reddy, Sekhar P.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130454/
https://ncbi.nlm.nih.gov/pubmed/27582105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00362.2016
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