Nrf2 mediates hypoxia-inducible HIF1α activation in kidney tubular epithelial cells

Nuclear factor erythroid 2-related factor 2 (Nrf2) and hypoxia-inducible factor-1α (HIF1α) transcription factors protect against ischemic acute kidney injury (AKI) by upregulating metabolic and cytoprotective gene expression. In this study, we tested the hypothesis that Nrf2 is required for HIF1α-me...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Potteti, Haranatha R., Noone, Patrick M., Tamatam, Chandramohan R., Ankireddy, Aparna, Noel, Sanjeev, Rabb, Hamid, Reddy, Sekhar P.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988808/
https://ncbi.nlm.nih.gov/pubmed/33491566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00501.2020
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