Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide

The synthetic oleanolic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Imidazolide or CDDO-Im) is an extremely potent activator of Nrf2 signaling. In cells undergoing adipogenesis, CDDO-Im prevents lipid accumulation in an Nrf2-dependent manner. However, in vivo evidenc...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Shin, Soona, Wakabayashi, Junko, Yates, Melinda S., Wakabayashi, Nobunao, Dolan, Patrick M., Aja, Susan, Liby, Karen T., Sporn, Michael B., Yamamoto, Masayuki, Kensler, Thomas W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752754/
https://ncbi.nlm.nih.gov/pubmed/19698707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.08.022
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky