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Allosteric Communication Pipelines in G-protein-coupled receptors

The binding of ligands to G-protein-coupled receptors (GPCRs) in the extracellular region transmits the signal to the intracellular region to initiate coupling to effector proteins. The mechanism of this allosteric communication remains largely unexplored. Knowledge of the residues involved in the p...

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Bibliografski detalji
Izdano u:Curr Opin Pharmacol
Glavni autori: Vaidehi, Nagarajan, Bhattacharya, Supriyo
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127785/
https://ncbi.nlm.nih.gov/pubmed/27497048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.07.010
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