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Allosteric Communication Pipelines in G-protein-coupled receptors

The binding of ligands to G-protein-coupled receptors (GPCRs) in the extracellular region transmits the signal to the intracellular region to initiate coupling to effector proteins. The mechanism of this allosteric communication remains largely unexplored. Knowledge of the residues involved in the p...

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Detalles Bibliográficos
Publicado en:Curr Opin Pharmacol
Main Authors: Vaidehi, Nagarajan, Bhattacharya, Supriyo
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127785/
https://ncbi.nlm.nih.gov/pubmed/27497048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.07.010
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