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Allosteric Communication Pipelines in G-protein-coupled receptors

The binding of ligands to G-protein-coupled receptors (GPCRs) in the extracellular region transmits the signal to the intracellular region to initiate coupling to effector proteins. The mechanism of this allosteric communication remains largely unexplored. Knowledge of the residues involved in the p...

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Bibliografische gegevens
Gepubliceerd in:Curr Opin Pharmacol
Hoofdauteurs: Vaidehi, Nagarajan, Bhattacharya, Supriyo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127785/
https://ncbi.nlm.nih.gov/pubmed/27497048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.07.010
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