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Allosteric Communication Pipelines in G-protein-coupled receptors

The binding of ligands to G-protein-coupled receptors (GPCRs) in the extracellular region transmits the signal to the intracellular region to initiate coupling to effector proteins. The mechanism of this allosteric communication remains largely unexplored. Knowledge of the residues involved in the p...

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Publicat a:Curr Opin Pharmacol
Autors principals: Vaidehi, Nagarajan, Bhattacharya, Supriyo
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127785/
https://ncbi.nlm.nih.gov/pubmed/27497048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.07.010
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