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Differences in Allosteric Communication Pipelines in the Inactive and Active States of a GPCR
G-protein-coupled receptors (GPCRs) are membrane proteins that allosterically transduce the signal of ligand binding in the extracellular (EC) domain to couple to proteins in the intracellular (IC) domain. However, the complete pathway of allosteric communication from the EC to the IC domain, includ...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4104064/ https://ncbi.nlm.nih.gov/pubmed/25028884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.015 |
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