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Differences in Allosteric Communication Pipelines in the Inactive and Active States of a GPCR

G-protein-coupled receptors (GPCRs) are membrane proteins that allosterically transduce the signal of ligand binding in the extracellular (EC) domain to couple to proteins in the intracellular (IC) domain. However, the complete pathway of allosteric communication from the EC to the IC domain, includ...

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Sonraí Bibleagrafaíochta
Main Authors: Bhattacharya, Supriyo, Vaidehi, Nagarajan
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104064/
https://ncbi.nlm.nih.gov/pubmed/25028884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.015
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