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Differences in Allosteric Communication Pipelines in the Inactive and Active States of a GPCR

G-protein-coupled receptors (GPCRs) are membrane proteins that allosterically transduce the signal of ligand binding in the extracellular (EC) domain to couple to proteins in the intracellular (IC) domain. However, the complete pathway of allosteric communication from the EC to the IC domain, includ...

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Detalhes bibliográficos
Main Authors: Bhattacharya, Supriyo, Vaidehi, Nagarajan
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104064/
https://ncbi.nlm.nih.gov/pubmed/25028884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.015
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