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Structural Insights into Conformational Stability of Wild-Type and Mutant β(1)-Adrenergic Receptor
Recent experiments to derive a thermally stable mutant of turkey beta-1-adrenergic receptor (β(1)AR) have shown that a combination of six single point mutations resulted in a 20°C increase in thermal stability in mutant β(1)AR. Here we have used the all-atom force-field energy function to calculate...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905111/ https://ncbi.nlm.nih.gov/pubmed/20643076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.075 |
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