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Ligand-Stabilized Conformational States of Human β(2) Adrenergic Receptor: Insight into G-Protein-Coupled Receptor Activation
G-protein-coupled receptors (GPCRs) are known to exist in dynamic equilibrium between inactive- and several active-state conformations, even in the absence of a ligand. Recent experimental studies on the β(2) adrenergic receptor (β(2)AR) indicate that structurally different ligands with varying effi...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2257890/ https://ncbi.nlm.nih.gov/pubmed/18065472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.117648 |
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