Ligand-Stabilized Conformational States of Human β(2) Adrenergic Receptor: Insight into G-Protein-Coupled Receptor Activation

G-protein-coupled receptors (GPCRs) are known to exist in dynamic equilibrium between inactive- and several active-state conformations, even in the absence of a ligand. Recent experimental studies on the β(2) adrenergic receptor (β(2)AR) indicate that structurally different ligands with varying effi...

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Bibliografiske detaljer
Main Authors: Bhattacharya, Supriyo, Hall, Spencer E., Li, Hubert, Vaidehi, Nagarajan
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Biophysical Theory and Modeling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257890/
https://ncbi.nlm.nih.gov/pubmed/18065472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.117648
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