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Allosteric Communication Pipelines in G-protein-coupled receptors

The binding of ligands to G-protein-coupled receptors (GPCRs) in the extracellular region transmits the signal to the intracellular region to initiate coupling to effector proteins. The mechanism of this allosteric communication remains largely unexplored. Knowledge of the residues involved in the p...

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Foilsithe in:Curr Opin Pharmacol
Main Authors: Vaidehi, Nagarajan, Bhattacharya, Supriyo
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127785/
https://ncbi.nlm.nih.gov/pubmed/27497048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.07.010
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