IGFBP-2 directly stimulates osteoblast differentiation

Insulin like growth factor binding protein two (IGFBP-2) is important for acquisition of normal bone mass in mice; however, the mechanism by which IGFBP-2 functions is not defined. These studies investigated the role of IGFBP-2 in stimulating osteoblast differentiation. MC-3T3 preosteoblasts express...

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Bibliographic Details
Published in:J Bone Miner Res
Main Authors: Xi, Gang, Wai, Christine, DeMambro, Victoria, Rosen, Clifford J, Clemmons, David R
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117190/
https://ncbi.nlm.nih.gov/pubmed/24839202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2282
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