The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity

door Clemmons, David R.
Gepubliceerd in 2004

Metabolic Actions of IGF-I in Normal Physiology and Diabetes

door Clemmons, David R.
Gepubliceerd in 2012

Blocking ligand occupancy of the αVβ3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

door Zheng, Bo, Clemmons, David R.
Gepubliceerd in 1998

AMP-Activated Protein Kinase Inhibits IGF-I Signaling and Protein Synthesis in Vascular Smooth Muscle Cells via Stimulation of Insulin Receptor Substrate 1 S794 and Tuberous Sclero...

door Ning, Junyu, Clemmons, David R.
Gepubliceerd in 2010

p66shc Negatively Regulates Insulin-Like Growth Factor I Signal Transduction via Inhibition of p52shc Binding to Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase Subst...

door Xi, Gang, Shen, Xinchun, Clemmons, David R.
Gepubliceerd in 2008

p66(shc) Inhibits Insulin-like Growth Factor-I Signaling via Direct Binding to Src through Its Polyproline and Src Homology 2 Domains, Resulting in Impairment of Src Kinase Activat...

door Xi, Gang, Shen, Xinchun, Clemmons, David R.
Gepubliceerd in 2010

Suppression of AMPK Activation via S485 Phosphorylation by IGF-I during Hyperglycemia Is Mediated by AKT Activation in Vascular Smooth Muscle Cells

door Ning, Junyu, Xi, Gang, Clemmons, David R.
Gepubliceerd in 2011

The current status of IGF-I assays – A 2009 update

door Frystyk, Jan, Freda, Pamela, Clemmons, David R.
Gepubliceerd in Growth Horm IGF Res (2009)

IGF-I and IGFBP-2 Stimulate AMPK Activation and Autophagy, Which Are Required for Osteoblast Differentiation

door Xi, Gang, Rosen, Clifford J., Clemmons, David R.
Gepubliceerd in Endocrinology (2016)

Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial

door Clemmons, David R., Miller, Sam, Mamputu, Jean-Claude
Gepubliceerd in PLoS One (2017)

The Association between Integrin-associated Protein and SHPS-1 Regulates Insulin-like Growth Factor-I Receptor Signaling in Vascular Smooth Muscle Cells

door Maile, Laura A., Badley-Clarke, Jane, Clemmons, David R.
Gepubliceerd in 2003

Dialyzable factor in human serum of platelet origin stimulates endothelial cell replication and growth

door Clemmons, David R., Isley, William L., Brown, M. Todd
Gepubliceerd in 1983

Identification of Novel SHPS-1-associated Proteins and Their Roles in Regulation of Insulin-like Growth Factor-dependent Responses in Vascular Smooth Muscle Cells

door Shen, Xinchun, Xi, Gang, Radhakrishnan, Yashwanth, Clemmons, David R.
Gepubliceerd in 2009

PDK1 Recruitment to the SHPS-1 Signaling Complex Enhances Insulin-like Growth Factor-I-stimulated AKT Activation and Vascular Smooth Muscle Cell Survival

door Shen, Xinchun, Xi, Gang, Radhakrishnan, Yashwanth, Clemmons, David R.
Gepubliceerd in 2010

The Coordinate Cellular Response to Insulin-like Growth Factor-I (IGF-I) and Insulin-like Growth Factor-binding Protein-2 (IGFBP-2) Is Regulated through Vimentin Binding to Recepto...

door Shen, Xinchun, Xi, Gang, Wai, Christine, Clemmons, David R.
Gepubliceerd in J Biol Chem (2015)

Hormonal Control of Immunoreactive Somatomedin Production by Cultured Human Fibroblasts

door Clemmons, David R., Underwood, Louis E., Van Wyk, Judson J.
Gepubliceerd in 1981

Recruitment of Nox4 to a Plasma Membrane Scaffold Is Required for Localized Reactive Oxygen Species Generation and Sustained Src Activation in Response to Insulin-like Growth Facto...

door Xi, Gang, Shen, Xin-Chun, Wai, Christine, Clemmons, David R.
Gepubliceerd in 2013

IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation

door Xi, Gang, Shen, Xinchun, Rosen, Clifford J, Clemmons, David R
Gepubliceerd in J Bone Miner Res (2016)

Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation

door Xi, Gang, Wai, Christine, White, Morris F., Clemmons, David R.
Gepubliceerd in J Biol Chem (2017)

A peptide containing the receptor binding site of insulin-like growth factor binding protein-2 enhances bone mass in ovariectomized rats

door Xi, Gang, Wai, Christine, Rosen, Clifford J., Clemmons, David R.
Gepubliceerd in Bone Res (2018)