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A peptide containing the receptor binding site of insulin-like growth factor binding protein-2 enhances bone mass in ovariectomized rats

Male Igfbp2−/− mice have a significant reduction in bone mass and administration of a peptide that contains the insulin-like growth factor binding protein-2(IGFBP-2) receptor-binding domain stimulates bone formation in these animals. Female Igfbp2−/− mice do not have this phenotype but following ova...

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Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Xi, Gang, Wai, Christine, Rosen, Clifford J., Clemmons, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089876/
https://ncbi.nlm.nih.gov/pubmed/30109160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-018-0024-9
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