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Insulin-like growth factor binding protein-2 is required for osteoclast differentiation
Global deletion of the Igfbp2 gene results in the suppression of bone turnover. To investigate the role of IGFBP-2 in regulating osteoclast differentiation we cultured Igfbp2(−/−) bone marrow cells and found a reduction in the number of osteoclasts and impaired resorption. Addition of full length IG...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3385417/ https://ncbi.nlm.nih.gov/pubmed/22006816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.545 |
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