The Coordinate Cellular Response to Insulin-like Growth Factor-I (IGF-I) and Insulin-like Growth Factor-binding Protein-2 (IGFBP-2) Is Regulated through Vimentin Binding to Receptor Tyrosine Phosphatase β (RPTPβ)

Insulin-like growth factor-binding protein-2 (IGFBP-2) functions coordinately with IGF-I to stimulate cellular proliferation and differentiation. IGFBP-2 binds to receptor tyrosine phosphatase β (RPTPβ), and this binding in conjunction with IGF-I receptor stimulation induces RPTPβ polymerization lea...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Shen, Xinchun, Xi, Gang, Wai, Christine, Clemmons, David R.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416861/
https://ncbi.nlm.nih.gov/pubmed/25787077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.620237
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