The Heparin-Binding Domains of IGFBP-2 Mediate Its Inhibitory Effect on Preadipocyte Differentiation and Fat Development in Male Mice

IGF-binding protein (IGFBP)-2 overexpression confers resistance to high-fat feeding and inhibits the differentiation of preadipocytes in vitro. However, whether administration of IGFBP-2 can regulate adipogenesis in vivo and the domains that mediate this response have not been defined. IGFBP-2 conta...

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Detalhes bibliográficos
Main Authors: Xi, Gang, Solum, Melissa A., Wai, Christine, Maile, Laura A., Rosen, Clifford J., Clemmons, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Energy Balance-Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800754/
https://ncbi.nlm.nih.gov/pubmed/23981772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1236
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