High-Affinity α-Conotoxin PnIA Analogs Designed on the Basis of the Protein Surface Topography Method

Despite some success for small molecules, elucidating structure–function relationships for biologically active peptides — the ligands for various targets in the organism — remains a great challenge and calls for the development of novel approaches. Some of us recently proposed the Protein Surface To...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Kasheverov, Igor E., Chugunov, Anton O., Kudryavtsev, Denis S., Ivanov, Igor A., Zhmak, Maxim N., Shelukhina, Irina V., Spirova, Ekaterina N., Tabakmakher, Valentin M., Zelepuga, Elena A., Efremov, Roman G., Tsetlin, Victor I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107951/
https://ncbi.nlm.nih.gov/pubmed/27841338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36848
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