טוען...
High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia
Activating NOTCH1 mutations are frequent in human T-cell acute lymphoblastic leukemia (T-ALL) and Notch inhibitors (γ-secretase inhibitors [GSIs]) have produced responses in patients with relapsed, refractory disease. However, sustained responses, although reported, are uncommon, suggesting that oth...
שמור ב:
| הוצא לאור ב: | Blood |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095757/ https://ncbi.nlm.nih.gov/pubmed/27670423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-692855 |
| תגים: |
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