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Notch signalling in T cell lymphoblastic leukaemia/lymphoma and other haematological malignancies

Notch receptors participate in a highly conserved signalling pathway that regulates normal development and tissue homeostasis in a context- and dose-dependent manner. Deregulated Notch signalling has been implicated in many diseases, but the clearest example of a pathogenic role is found in T cell l...

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Autors principals: Aster, Jon C., Blacklow, Stephen C., Pear, Warren S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996483/
https://ncbi.nlm.nih.gov/pubmed/20967796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2789
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