Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling

Constitutive NOTCH signaling in lymphoid progenitors promotes the development of immature T-cell lymphoblastic neoplasms (T-ALLs). Although it is clear that Notch signaling can initiate leukemogenesis, it has not previously been established whether continued NOTCH signaling is required to maintain T...

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Autors principals: Weng, Andrew P., Nam, Yunsun, Wolfe, Michael S., Pear, Warren S., Griffin, James D., Blacklow, Stephen C., Aster, Jon C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151540/
https://ncbi.nlm.nih.gov/pubmed/12509463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.655-664.2003
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