Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling

Constitutive NOTCH signaling in lymphoid progenitors promotes the development of immature T-cell lymphoblastic neoplasms (T-ALLs). Although it is clear that Notch signaling can initiate leukemogenesis, it has not previously been established whether continued NOTCH signaling is required to maintain T...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Weng, Andrew P., Nam, Yunsun, Wolfe, Michael S., Pear, Warren S., Griffin, James D., Blacklow, Stephen C., Aster, Jon C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2003
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509463/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.655-664.2003
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