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Notch Signaling in Leukemia
Recent discoveries indicate that gain-of-function mutations in the Notch1 receptor are very common in human T cell acute lymphoblastic leukemia/lymphoma. This review discusses what these mutations have taught us about normal and pathophysiologic Notch1 signaling, and how these insights may lead to n...
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| Publicado no: | Annu Rev Pathol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934586/ https://ncbi.nlm.nih.gov/pubmed/18039126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev.pathmechdis.3.121806.154300 |
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