Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis Polymerases

DNA-protein cross-links (DPCs) are bulky DNA lesions that form both endogenously and following exposure to bis-electrophiles such as common antitumor agents. The structural and biological consequences of DPCs have not been fully elucidated due to the complexity of these adducts. The most common site...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Biol Chem
المؤلفون الرئيسيون: Wickramaratne, Susith, Ji, Shaofei, Mukherjee, Shivam, Su, Yan, Pence, Matthew G., Lior-Hoffmann, Lee, Fu, Iwen, Broyde, Suse, Guengerich, F. Peter, Distefano, Mark, Schärer, Orlando D., Sham, Yuk Yin, Tretyakova, Natalia
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2016
الموضوعات:
DNA and Chromosomes
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095413/
https://ncbi.nlm.nih.gov/pubmed/27621316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745257
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