A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson–Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4)

Por Wang, Lihua, Broyde, Suse
Publicado em 2006

Influence of local sequence context on damaged base conformation in human DNA polymerase ι: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived...

Por Donny-Clark, Kerry, Broyde, Suse
Publicado em 2009

How to accurately bypass damage

Por Broyde, Suse, Patel, Dinshaw J.
Publicado no Nature (2010)

Polymerase-tailored variations in the Water-Mediated and Substrate-Assisted Mechanism for Nucleotidyl Transfer: Insights from a Study of T7 DNA Polymerase

Por Wang, Lihua, Broyde, Suse, Zhang, Yingkai
Publicado em 2009

The N-clasp of human DNA polymerase κ promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions

Por Jia, Lei, Geacintov, Nicholas E., Broyde, Suse
Publicado em 2008

Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase ι: Hoogsteen or Watson-Crick base pairing?

Por Donny-Clark, Kerry, Shapiro, Robert, Broyde, Suse
Publicado em 2009

Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions

Por Cai, Yuqin, Geacintov, Nicholas E., Broyde, Suse
Publicado em 2012

Ribonucleotides as nucleotide excision repair substrates

Por Cai, Yuqin, Geacintov, Nicholas E., Broyde, Suse
Publicado no DNA Repair (Amst) (2013)

DNA Damage, Mutagenesis, and DNA Repair

Por Basu, Ashis, Broyde, Suse, Iwai, Shigenori, Kisker, Caroline
Publicado em 2010

Lesion Specificity in the Base Excision Repair Enzyme hNeil1: Modeling and Dynamics Studies

Por Jia, Lei, Shafirovich, Vladimir, Geacintov, Nicholas E., Broyde, Suse
Publicado em 2007

4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site and structure

Por Ding, Shuang, Shapiro, Robert, Geacintov, Nicholas E., Broyde, Suse
Publicado em 2007

Intercalative Conformations of the 14R (+)- and 14S (–)-trans-anti-DB[a,l]P-N(6)-dA Adducts: Molecular Modeling and MD Simulations

Por Cai, Yuqin, Ding, Shuang, Geacintov, Nicholas E., Broyde, Suse
Publicado em 2011

Recognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched cis-syn Thymine Dimer Lesion

Por Mu, Hong, Geacintov, Nicholas E., Zhang, Yingkai, Broyde, Suse
Publicado no Biochemistry (2015)

A Water-mediated and Substrate-assisted Catalytic Mechanism for Sulfolobus solfataricus DNA Polymerase IV

Por Wang, Lihua, Yu, Xinyun, Hu, Po, Broyde, Suse, Zhang, Yingkai
Publicado em 2007

Transcription elongation past O(6)-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase

Por Dimitri, Alexandra, Burns, John A., Broyde, Suse, Scicchitano, David A.
Publicado em 2008

Differential Nucleotide Excision Repair Susceptibility of Bulky DNA Adducts in Different Sequence Contexts: Hierarchies of Recognition Signals

Por Cai, Yuqin, Patel, Dinshaw J., Geacintov, Nicholas E., Broyde, Suse
Publicado em 2008

Base Sequence Context Effects on Nucleotide Excision Repair

Por Cai, Yuqin, Patel, Dinshaw J., Broyde, Suse, Geacintov, Nicholas E.
Publicado em 2010

Dynamics of a Benzo[a]pyrene-derived Guanine DNA Lesion in TGT and CGC Sequence Contexts: Enhanced Mobility in TGT Explains Conformational Heterogeneity, Flexible Bending, and Grea...

Por Cai, Yuqin, Patel, Dinshaw J., Geacintov, Nicholas E., Broyde, Suse
Publicado no J Mol Biol (2007)

Following an environmental carcinogen N(2)-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase

Por Xu, Pingna, Oum, Lida, Beese, Lorena S., Geacintov, Nicholas E., Broyde, Suse
Publicado em 2007

Flexible 5-Guanidino-4-nitroimidazole DNA Lesions: Structures and Thermodynamics

Por Jia, Lei, Shafirovich, Vladimir, Shapiro, Robert, Geacintov, Nicholas E., Broyde, Suse
Publicado em 2006