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Differential Nucleotide Excision Repair Susceptibility of Bulky DNA Adducts in Different Sequence Contexts: Hierarchies of Recognition Signals
The structural origin underlying differential nucleotide excision repair (NER) susceptibilities of bulky DNA lesions remains a challenging problem. As a model system, we investigate the 10S (+)-trans-anti-[BP]-N(2)-dG (G*) adduct in double-stranded DNA. This adduct arises from the reaction, in vitro...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680230/ https://ncbi.nlm.nih.gov/pubmed/18948114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.09.087 |
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