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Differential Nucleotide Excision Repair Susceptibility of Bulky DNA Adducts in Different Sequence Contexts: Hierarchies of Recognition Signals

The structural origin underlying differential nucleotide excision repair (NER) susceptibilities of bulky DNA lesions remains a challenging problem. As a model system, we investigate the 10S (+)-trans-anti-[BP]-N(2)-dG (G*) adduct in double-stranded DNA. This adduct arises from the reaction, in vitro...

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書誌詳細
主要な著者: Cai, Yuqin, Patel, Dinshaw J., Geacintov, Nicholas E., Broyde, Suse
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680230/
https://ncbi.nlm.nih.gov/pubmed/18948114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.09.087
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