Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function

The nucleotide excision repair of certain bulky DNA lesions is abrogated in some specific non-canonical DNA base sequence contexts, while the removal of the same lesions by the nucleotide excision repair mechanism is efficient in duplexes in which all base pairs are complementary. Here we show that...

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Bibliographic Details
Published in:PLoS One
Main Authors: Liu, Zhi, Ding, Shuang, Kropachev, Konstantin, Lei, Jia, Amin, Shantu, Broyde, Suse, Geacintov, Nicholas E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560436/
https://ncbi.nlm.nih.gov/pubmed/26340000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137124
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