Adenine-DNA adducts derived from the highly tumorigenic dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not

The structural origins of differences in susceptibilities of various DNA lesions to nucleotide excision repair (NER) are poorly understood. Here we compared, in the same sequence context, the relative NER dual incision efficiencies elicited by two stereochemically distinct pairs of guanine (N(2)-dG)...

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Detalhes bibliográficos
Main Authors: Kropachev, Konstantin, Kolbanovskiy, Marina, Liu, Zhi, Cai, Yuqin, Zhang, Lu, Schwaid, Adam G., Kolbanovskiy, Alexander, Ding, Shuang, Amin, Shantu, Broyde, Suse, Geacintov, Nicholas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676272/
https://ncbi.nlm.nih.gov/pubmed/23570232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400080k
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