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Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function

The nucleotide excision repair of certain bulky DNA lesions is abrogated in some specific non-canonical DNA base sequence contexts, while the removal of the same lesions by the nucleotide excision repair mechanism is efficient in duplexes in which all base pairs are complementary. Here we show that...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Liu, Zhi, Ding, Shuang, Kropachev, Konstantin, Lei, Jia, Amin, Shantu, Broyde, Suse, Geacintov, Nicholas E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560436/
https://ncbi.nlm.nih.gov/pubmed/26340000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137124
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