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Transcription elongation past O(6)-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase
O(6)-Methylguanine (O(6)-meG) is a major mutagenic, carcinogenic and cytotoxic DNA adduct produced by various endogenous and exogenous methylating agents. We report the results of transcription past a site-specifically modified O(6)-meG DNA template by bacteriophage T7 RNA polymerase and human RNA p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582612/ https://ncbi.nlm.nih.gov/pubmed/18854351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn657 |
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