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Transcriptional Bypass of DNA-protein and DNA-peptide Conjugates by T7 RNA Polymerase
DNA-protein cross-links (DPCs) are unusually bulky DNA adducts that block the access of proteins to DNA and interfere with gene expression, replication, and repair. We previously described DPC formation at the N7-guanine position of DNA in human cells treated with antitumor nitrogen mustards and pla...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8177100/ https://ncbi.nlm.nih.gov/pubmed/31573793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00365 |
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