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Transcriptional Bypass of DNA-protein and DNA-peptide Conjugates by T7 RNA Polymerase

DNA-protein cross-links (DPCs) are unusually bulky DNA adducts that block the access of proteins to DNA and interfere with gene expression, replication, and repair. We previously described DPC formation at the N7-guanine position of DNA in human cells treated with antitumor nitrogen mustards and pla...

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Bibliografski detalji
Izdano u:ACS Chem Biol
Glavni autori: Ji, Shaofei, Thomforde, Jenna, Rogers, Colette, Fu, Iwen, Broyde, Suse, Tretyakova, Natalia Y.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177100/
https://ncbi.nlm.nih.gov/pubmed/31573793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00365
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