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Transcription Processing at 1,N(2)-ethenoguanine by Human RNA Polymerase II and Bacteriophage T7 RNA Polymerase

The DNA lesion 1,N(2)-ethenoguanine is formed endogenously as a byproduct of lipid peroxidation or by reaction with epoxides that result from the metabolism of the industrial pollutant vinyl chloride, a known human carcinogen. DNA replication past 1,N(2)-ethenoguanine and site specific mutagenesis s...

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Detalhes bibliográficos
Main Authors: Dimitri, Alexandra, Goodenough, Angela K., Guengerich, F. Peter, Broyde, Suse, Scicchitano, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262288/
https://ncbi.nlm.nih.gov/pubmed/18022639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.10.057
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