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Flexible 5-Guanidino-4-nitroimidazole DNA Lesions: Structures and Thermodynamics

5-Guanidino-4-nitroimidazole (NI), derived from guanine oxidation by reactive oxygen and nitrogen species, contains an unusual flexible ring opened structure, with nitro and guanidino groups which possess multiple hydrogen bonding capabilities. In vitro primer extension experiments with bacterial an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jia, Lei, Shafirovich, Vladimir, Shapiro, Robert, Geacintov, Nicholas E., Broyde, Suse
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527740/
https://ncbi.nlm.nih.gov/pubmed/16716075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0601757
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