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Flexible 5-Guanidino-4-nitroimidazole DNA Lesions: Structures and Thermodynamics

5-Guanidino-4-nitroimidazole (NI), derived from guanine oxidation by reactive oxygen and nitrogen species, contains an unusual flexible ring opened structure, with nitro and guanidino groups which possess multiple hydrogen bonding capabilities. In vitro primer extension experiments with bacterial an...

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Detalhes bibliográficos
Main Authors: Jia, Lei, Shafirovich, Vladimir, Shapiro, Robert, Geacintov, Nicholas E., Broyde, Suse
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527740/
https://ncbi.nlm.nih.gov/pubmed/16716075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0601757
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