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Simulating Structural and Thermodynamic Properties of Carcinogen-Damaged DNA

A pair of stereoisomeric covalent adducts to guanine in double-stranded DNA, derived from the reaction of mutagenic and tumorigenic metabolites of benzo[a]pyrene, have been well characterized structurally and thermodynamically. Both high-resolution NMR solution structures and an array of thermodynam...

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Detalhes bibliográficos
Main Authors: Yan, Shixiang, Wu, Min, Patel, Dinshaw J., Geacintov, Nicholas E., Broyde, Suse
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302781/
https://ncbi.nlm.nih.gov/pubmed/12668423
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