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Proteolytic maturation of α(2)δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels
The auxiliary α(2)δ subunits of voltage-gated calcium channels are extracellular membrane-associated proteins, which are post-translationally cleaved into disulfide-linked polypeptides α(2) and δ. We now show, using α(2)δ constructs containing artificial cleavage sites, that this processing is an es...
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出版年: | eLife |
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主要な著者: | , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
eLife Sciences Publications, Ltd
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5092059/ https://ncbi.nlm.nih.gov/pubmed/27782881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21143 |
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